Molecular Details
DICL_CP_0327085
- 2-phenyl-4-(propan-2-ylamino)-2-pyridin-2-ylbutanamide
Basic Molecular Information
Basic Information
DICL ID
DICL_CP_0327085
PubChem CID
Molecular Formula
C18H23N3O Molecular Weight
297.402 g/mol
Synonyms/Alias
[38236-46-3; 4-(Isopropylamino)-2-(2-pyridyl)-2-phenylbutyramide; Mono-isopropyl-disopyramide; 2-phenyl-4-(propan-2-ylamino)-2-pyridin-2-ylbutanamide; T4H9FLX72T; 4-Isopropylamino-2-phenyl-2-(2-pyridy...
InChI Key
UWNSWIXIVDMCHZ-UHFFFAOYSA-N
InChI
InChI=1S/C18H23N3O/c1-14(2)20-13-11-18(17(19)22,15-8-4-3-5-9-15)16-10-6-7-12-21-16/h3-10,12,14,20H,1...
IUPAC Name
2-phenyl-4-(propan-2-ylamino)-2-pyridin-2-ylbutanamide
CAS Number
38236-46-3
Structure Information
Chemical Structure Visualization
SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF
45 46 0 0 0 0 0 0 0 0999 V2000
4.9809 -0.9415 0.2207 C 0 0 0 0 0 0 0 0 0 0 0 0
3.6958 -0.3038 -0.3287 C 0 0 0 0 0 0 0 0 0 0 0 0
3.9716 1.161...
Experimental Data
Activity Data
Target Ion Channel
Inward rectifier potassium channel 2
Uniprot Accession Number
Function
Inactive
Species
Homo sapiens (Human)
IC50
N/A (Not available)
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
No effect
Experimental Conditions
pH
pH 7.4
Holding Potential
−80 mV mV
Temperature
22–24 °C
Test Method
Patch-clamping
Test Species
MIN6 cell
Binding Information
Binding Site
Not specified
Binding Site Residue
Not specified
Disease Information
Related Disease
Not specified
References
Computed Properties
Heavy Atom Count
22
Rotatable Bonds
7
logP
2.2411
Complexity
88.4091
TPSA (Ų)
68.01
H-Bond Donors
2
H-Bond Acceptors
3
Ring Count
2